Abstract
In this study we recorded the myoelectric activity in opossums' sphincter of Oddi (SO) and gastrointestinal tracts, in conscious state, using chronically implanted electrodes. Bipolar electrodes were implanted in the gastric antrum, duodenum, SO segment, jejunum and ileum. During fasting the frequency of SO spike bursts showed a cyclic pattern consisting of four phases (A-D). There is a very close relationship between the interdigestive migrating myoelectric complex (MMC) of the gastrointestinal tract and the SO activity. The ontet to phase C in the SO, characterized by a maximal spike burst frequency, began 1-2 min before phase III of MMC activity in the duodenum, The phase activity from the gastric antrum and phase C activity from the SO propagated so as to meet at the choledochoduodenal junction.During fasting CCK-OP and pentagastrin increased the SO spike burst frequency and abolished the periodically recurring pattern in the gastrointestinal tract and SO.After feeding the SO spike burst frequency began to increase quickly and lasted for at least 3 h.In conclusion, during fasting there exists a very close relationship between MMC and SO activity in opossums, but the physiological role of the relationship and the control mechanisms remain to be determined.
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