Mortality among critical care patients with autoimmune diseases at a tertiary care center in Bogotá, Colombia

Abstract

Event Abstract Back to Event Mortality among critical care patients with autoimmune diseases at a tertiary care center in Bogotá, Colombia Jorge A. Carrizosa1, Alexander Sanchez2*, Eduardo De Zubiria3 and Alberto De Zubiria2 1 Rosario University, Critical and intensive care medicine, Colombia 2 Samaritana´s University Hospital, Colombia 3 Sabana´s University, Colombia Background: Autoimmune diseases are not the first diagnoses between patients in critical care units; however those ones have significantly high mortality rates. The purpose of this study was research for risk factors related to mortality in this group of patients in critical care unit at the Samaritana´s University Hospital. Methods: We conducted a single center, retrospective case-control study, based on medical records review from patients hospitalized in the critical care unit with diagnosis of an autoimmune disease at the Samaritana´s University Hospital. We collect 68 patients and the primary end point was mortality. Results: Autoimmune diseases were more frequently among women (66%), systemic lupus erythematosus was the most common disease (36%), clinical and laboratory criteria were met in 77% cases, average age was 46 years old, the mean for days in mechanical ventilation was 10 days (SD 13 days), mean for APACHE II score was 19 points, the organic system more frequently affected was renal system (58,5%), global mortality rate was 40%. Mortality risk significantly increased among patients with shock (OR: 7.368; 95% CI, 1.886 to 28.794); procalcitonin level over 10 ng/ml (OR: 5.231 95% CI, 1.724 to 15.869); C3 complement under normal (OR: 4.014 95% CI, 1.223 to 13.173); serositis on chest X ray (OR: 3.771 95% CI, 1.238 to 11.492); and platelet count below 100.000 (OR: 3.33 95% CI, 1.037 to 10.714). Conclusions: There are factors that could be related to mortality in patients with autoinmune diseases who are critically ill. To identify as soon as possible those factors would be accompanied with a better prognosis. Acknowledgements Special acknowledgements to Dr. Maria Teresa García and staff in the critical care unit at the Samaritana´s Hospital. Keywords: Autoimmune Diseases, Critical Care, Mortality, Risk factors, Colombia Conference: IMMUNOCOLOMBIA2015 - 11th Congress of the Latin American Association of Immunology - 10o. Congreso de la Asociación Colombiana de Alergia, Asma e Inmunología, Medellin, Colombia, 13 Oct - 16 Oct, 2015. Presentation Type: Poster Presentation Topic: Autoimmunity Citation: Carrizosa JA, Sanchez A, De Zubiria E and De Zubiria A (2015). Mortality among critical care patients with autoimmune diseases at a tertiary care center in Bogotá, Colombia. Front. Immunol. Conference Abstract: IMMUNOCOLOMBIA2015 - 11th Congress of the Latin American Association of Immunology - 10o. Congreso de la Asociación Colombiana de Alergia, Asma e Inmunología. doi: 10.3389/conf.fimmu.2015.05.00203 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 15 Apr 2015; Published Online: 14 Sep 2015. * Correspondence: Dr. Alexander Sanchez, Samaritana´s University Hospital, Bogota, Bogota, 11001000, Colombia, alejiler@yahoo.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Jorge A Carrizosa Alexander Sanchez Eduardo De Zubiria Alberto De Zubiria Google Jorge A Carrizosa Alexander Sanchez Eduardo De Zubiria Alberto De Zubiria Google Scholar Jorge A Carrizosa Alexander Sanchez Eduardo De Zubiria Alberto De Zubiria PubMed Jorge A Carrizosa Alexander Sanchez Eduardo De Zubiria Alberto De Zubiria Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.