Abstract
The work is devoted to the study of the influence of socio-emotional stress of mothers at different stages ofpregnancy on the formation of adipose tissue in female offspring in adulthood, the detection of the presence andnature of the influence of additional stress factors on morphofunctional characteristics of adipose tissue in theseanimals. In an experiment on Wistar rats population, body weight, visceral and separately mesenteric adipose tissue weight in 12-month-old offspring of gestational stressed mothers were determined. It has been shown thatadult offspring of stressed mothers have increased body weight and visceral adipose tissue mass compared tooffspring of intact mothers. A comparative study of morphometric data of mesenteric adipose tissue in femalerats — offspring of intact and gestational stressed mothers in a state of physiological rest and after action ofstress factors was carried out. Thus, it can be said that already in a state of physiological rest there are quantitativeand qualitative differences between the cellular composition of mesenteric adipose tissue of intact(control) and test female offspring. Additional stress in the adult state particularly clearly affected the cellularcomposition and its characteristics in offspring of gestational stressed females. There has been an increase inthe number of average size adipocytes in gr C-1s with a simultaneous expressive increase in the number of largeand very large adipocytes, indicating the development of hypertrophic obesity in animals of this group. At thesame time, the prevalence of the percentage of small and medium adipocytes in gr C-3s after exposure to stressfactors indicates active hyperplastic processes in the mesenteric adipose tissue of these rats. The manifestationof hyperplasia activity is also the appearance of numerous small size adipocyte formations in the adipose tissueof this group of descendants. It has been found that stress of sexually mature offspring leads to the formation ofa hypertrophic type of obesity in intact animals and offspring of mothers stressed in the first trimester of pregnancy and provokes hyperplasia of adipocytes and the appearance of signs of inflammation of adipose tissue in rats stressed in the antenna period.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
