Abstract

Introduction: The orbit is a bone cavity in the skull. Its morphological and anthropological knowledge is essential, as it is a region subjected to several surgical procedures. Objective: To analyze the morphology of orbits in the skulls of two populations in Northeastern Brazil Methods: 115 skulls belonging to Federal University of Paraíba (UFPB) and Federal University of Ceará (UFC) were analyzed. The skulls were categorized into three types: Megaseme, Mesoseme and Microseme. Quantitative analysis included these measurements: orbital height (OH), Orbital Breadth (OB) and index orbital (OI). Data were prepared for statistical analysis using IBM SPSS 23 software, with a significance level of 5%. Results: 58 skulls (50.4%) were female and 57 (49.6%) were male. The sample consisted of 91 (79.1%) skulls from UFPB and 24 (20.9%) from UFC. At UFPB, 85.16% of the orbits were Microseme, 12.64%, Mesoseme and 2.2%, Megaseme. In the UFC, 58.3% were Microseme, 25%, Mesoseme and 16.7%, Megaseme. Considering both populations, 79.6% of the orbits were microseme, 15.2%, mesoseme and 5.2%, megaseme. There were no differences in morphometric parameters between the orbits (p> 0.05). When comparing the two populations studied, there were significant differences in the variables OI and OB (p <0.05). Conclusions: Orbits were of the Microseme type. No difference between the height of the UFC and UFPB orbits was found, however, there was a difference in OI and OB. These regional differences corroborate the clinical and surgical importance of the morphological study of the orbit, as it undergoes changes depending on the population.

Highlights

  • Capsaicin is able to induce mast cell degranulation, an event probably related to the pathophysiology of a migraine attack

  • The present review study aimed to address the mechanisms of action of capsaicin and other chemical inducers in mast cell degranulation and an interaction of nerves and events that happen in the dura mater with the activation of mast cells

  • Conclusion: the analyzed data indicate that the polymorphisms contributed to the susceptibility to Parkinson’s disease (PD), further studies related to the polymorphisms and their relationship to PD are still needed for more ethnic groups, and early diagnosis is possible

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Summary

Introduction

Capsaicin is able to induce mast cell degranulation, an event probably related to the pathophysiology of a migraine attack. Methods: A literature review and an observational, descriptive and transversal data collect on treatment for acute demyelinating polyradiculoneuritis, available at DATASUS from January 2008 to December 2020, and articles available at Scielo and PubMed. Results: There were 7,917 hospitalizations, representing a total expenditure of R$ 9,392,552.04, 2009 being the year with the highest number of hospitalizations (809) and 2017 with the highest amount spent during the period (R$ 967,284.65). Methods: A literature review and an observational, descriptive and transversal data collect on surgical treatment was carried out, available from January 2008 to December 2020 and articles available in Scielo, Lilacs and PubMed. Results: There were 15,148 hospitalizations for surgical procedures for the treatment of chronic subdural hematoma, representing a total expenditure of R$ 45,365,258.21, with 2018 being the year with the highest number of hospitalizations (1,418) and with the highest amount spent during the period (R$ 4,570,334.28). Conclusions: The “Coca-Cola Bottle sign” is a classic sign of Graves’ disease, some signs, such as, unilateral and single orbital musculature involvement, may be suggestive of involvement by other etiologies, suggesting the benefit of an early expanded investigation

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