Abstract

Abstract Electrochemical sensor for the determination of Vitamin B 12 was fabricated using a disposable pencil graphite electrode. The main highlight of this work is that without any electrode modification and analyte pre-concentration, direct electrochemical detection of Vitamin B 12 was made possible. Morphological and structural studies were incorporated. Electrochemical studies were done using cyclic voltammetry and differential pulse voltammetry. Electrochemical reduction of Vitamin B 12 was observed at -0.82 V. Sensor exhibited a linear range of 2.5-30 nM with a sensitivity of 1.96 µA/nM/cm2. The viability of the sensor towards practical use was tested in commercial Vitamin B 12 tablet.

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