MORPHOLOGICAL STRUCTURE OF THE HUMERUS WITH IMPLANTATION INTO THE TIBIAL BONE HYDROXYAPATITE MATERIAL OC-015, ALLOYED BY MANGANESE

Abstract

In the experiment on 252 albino rats with initial body weight of 135-145g it is established, that making the defect 2,2 mm in diameter on the border of proximal metaphysis and diaphysis of the tibial bone is accompanied by decrease of a mechanical strength of the humeral bones. At the same time the amplitude of deviations depends on the degree of activity of reparative regeneration processes. Implantation of biogenic hydroxylapatite ОC- 015 into the area of defect is accompanied by similar deviations which are completely leveled to the late terms of observation. Implantation of ОC-015 into the osseous defect, alloyed by manganese, substantially smoothes the deviations found.