Abstract

This study was designed to serve as a standard for experiments studying effects of behavior or other variables on the anatomy of the rat brain. The depth of the cerebral cortex, the hippocampus, and the diencephalon were measured, as well as the width of the diencephalon, in male, Long-Evans rats in the following age groups: 6, 10, 14, 20, 26, 41, 55, 77, 90, 108, 185, 300, 400, and 650 days. In general, the depth of all the forebrain structures increases to 26 days of age at which time the cerebral cortex decreases while the hippocampus and diencephalon continue to increase until 650 days of age. A search for hemispheric dominance in the rat showed the right cerebral cortex to be thicker than the left in all age groups in 92 out of 98 areas measured. The body weights and endocrine organ weights were recorded.

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