Morphological assessment of osseointegration during replacement of mandible defect with implants that made using additive technologies. Experimental research

Abstract

According to the pre-made patterns of 3D-design and prototyping patterns during the experiment, defects of the lateral portion of the ram's lower jaw were created using the piezosurgical technique. The defects were replaced by plastic implants obtained by the method of layer-by-layer melting of FDM-printing (fusing deposition modeling, FDM) and fixing titanium screws to the jaw body. In the time interval, plastic implants are replaced by titanium ones, obtained using SLS technology -selective laser sintering using a 3D-printer. In order to study the processes of reparative osteogenesis, microsamples of tissues of the periimplantation zone were analyzed. As a result, signs of osteo- and fibro-osseointegration were identified. The data obtained are regarded as a prerequisite for further clinical trials of the developed protocols for the sequential replacement of defects of the jaws using 3D-printing.