Abstract
A histologic and morphometric study of the structure of the major saphenous vein at various levels in 45 patients aged 21 to 65 years is conducted. Microscopic study of varicose vein wall showed that its changes consist of multiple reconstructing processes including all its layers. Morphometric analysis detected the biggest thickness of the intima in the first group of the lower third of the shin. Its thickness decreases with age. The lowest index was found in the third group of patients of the lower third of the shin. Peculiarities of the structural changes in the venous wall of the major saphenous vein are of special importance both for pre-operation preparation to choose such minor invasive surgical methods as sclerosing and endovascular laser coagulation of veins and prevention of recurrent varicose diseases of the lower extremities.
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