Abstract

Urine protein electrophoresis (UPE) and immunofixation (uIF) are central in the diagnosis and follow up of patients with monoclonal gammopathies. They allow: proteinuria screening, urine peak typing and quantification. Peak quantification is an important criterion used for response to treatment assessment for multiple myeloma patients. International Myeloma Working Group (IMWG) guidelines recommend 24 hour (24h) urine testing. In front of difficulties of 24h urine collection, and since proof of analyzes on morning urine is lacking, we decided to compare data from both morning and 24h urines.

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