MP26-03 24-HOUR URINE TEST CONTRIBUTES TO THE DECREASED RISK OF RECURRENT STONE EVENTS

Abstract

You have accessJournal of UrologyCME1 May 2022MP26-03 24-HOUR URINE TEST CONTRIBUTES TO THE DECREASED RISK OF RECURRENT STONE EVENTS Rei Unno, Xavier Cortez, Leslie Charondo, Kevin Chang, Nizar Hakam, Carter Chan, Heiko Yang, Gregory Hosier, Fadl Hamouche, David Bayne, Marshall Stoller, and Thomas Chi Rei UnnoRei Unno More articles by this author , Xavier CortezXavier Cortez More articles by this author , Leslie CharondoLeslie Charondo More articles by this author , Kevin ChangKevin Chang More articles by this author , Nizar HakamNizar Hakam More articles by this author , Carter ChanCarter Chan More articles by this author , Heiko YangHeiko Yang More articles by this author , Gregory HosierGregory Hosier More articles by this author , Fadl HamoucheFadl Hamouche More articles by this author , David BayneDavid Bayne More articles by this author , Marshall StollerMarshall Stoller More articles by this author , and Thomas ChiThomas Chi More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002569.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Although the AUA guideline recommends metabolic testing in first-time stone formers with high-risks and recurrent stone formers, this is not often followed in real world practice. This study aimed to understand the characteristics of patients undergoing 24-hour (24h) urine testing, as well as the direct impact of the metabolic testing on the changes in stone burden/number and recurrent stone events during follow-up. METHODS: This was an analysis of prospectively collected data from the Registry for Stones of the Kidney and Ureter (ReSKU) from a single institution between October 2015 and May 2021. We compared demographics and clinical information between individuals with a 24h urine test and those without a test. We also collected data on changes in stone burden/number and stone events during the period from the initial clinic visit to the next clinic visit. Univariate and multivariate logistic regression analyses were performed to identify the factors associated with the clinical severity of urolithiasis. RESULTS: Of 1921 patients analyzed, 564 patients (29.3%) underwent a 24h urine test. Patients who agreed to perform a 24h urine test were more often highly educated, non-smokers, and had hyperlipidemia (HL), a past stone history and a positive family history of urolithiasis. They also were more likely to present with a higher stone burden and bilateral stones. Over a median follow-up period of 5 months, those with a 24h urine testing were less likely to have an increase their stone burden and number on imaging and experience stone events than those without a 24h urine test. On multivariate analysis, undergoing a 24h urine test remained a statistically significant factor decreasing the risks of an increase in stone burden and number and recurrent stone events (OR 0.57 p<0.001, OR 0.68 p=0.035, respectively) (Table1). CONCLUSIONS: Consistent with the AUA guidelines, when metabolic testing was performed in patients with high-risk for stone recurrence these patients experienced fewer recurrent stone events. These data support that metabolic testing should be performed more frequently in patients with first time kidney stones. Source of Funding: none © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e439 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Rei Unno More articles by this author Xavier Cortez More articles by this author Leslie Charondo More articles by this author Kevin Chang More articles by this author Nizar Hakam More articles by this author Carter Chan More articles by this author Heiko Yang More articles by this author Gregory Hosier More articles by this author Fadl Hamouche More articles by this author David Bayne More articles by this author Marshall Stoller More articles by this author Thomas Chi More articles by this author Expand All Advertisement PDF DownloadLoading ...