Monitoring of Occurrence of Thyroid Gland Disorders in Human Population in Industrial Regions

Abstract

PP-31-139 Background/Aims: Thyroid disorders are the most common endocrinologic diseases. Hypo- and hyperfunction of thyroid gland affects metabolic processes in the body causing different damages to human health. Methods: The incidence of the most common diseases of thyroid gland was studied directly in the endocrine clinics. We studied a sample of 24,928 patients during 8 years in 2 different areas of eastern Slovakia—Prešov and Košice region. Both regions are highly industrially exposed. In studied sample, we focused on the incidence of thyrotoxicosis, hypothyroidism, thyroiditis, and malignant thyroid tumors. Results: In the research we found the following results: The incidence of thyrotoxicosis (133 cases in 2000, 86 cases in 2008) and thyroiditis (1401 patients in 2000, 739 in 2008) had a downward trend in Košice region. The increase in Košice region was monitored in patients with hyperthyreosis (479 in 2000, 618 in 2008) and malignant thyroid tumors (62 in 2000 and 91 in 2008). In Prešov region, the increased incidence of all observed diseases of thyroid gland—thyrotoxicosis (52 in 2000, 154 in 2008), hypothyroidism (345 in 2000, 844 in 2008), thyroiditis (1208 in 2000, 1989 in 2008), and malignant neoplasms (15 in 2000, 68 in 2008) was found. Conclusion: Hypothyroidism, hyperthyroidism, thyroiditis, and thyrotoxicosis are generally declining, in opposition with the malignant tumor of the thyroid gland which records the increase. According to the results, we recommend the medical practice to include the examination of thyroid gland into standard preventive examination. This research is supported by the Agency of Ministry of Education SR for the Structural Funds of the EU, the project: ITMS 26220120023.