Molecularly imprinted polymers of allyl-β-cyclodextrin and methacrylic acid for the solid-phase extraction of phthalate

Abstract

β-Cyclodextrin was derived by allylic bromine (allyl-β-CD). A new kind of molecularly imprinted polymers (MIPs) with selective adsorption for phthalate were prepared using allyl-β-CD and methacrylic acid (MAA) as the binary functional monomers. The allyl-β-CD-MIPs were characterized by scanning electron micrograph (SEM) and Fourier transform-infrared spectroscopy (FT-IR). In this work, dipentyl phthalate (DPP) was selected as template; the interaction of DPP with MAA, acrylamide (AM) and methyl methacrylate (MMA) were compared by UV spectroscopic techniques. Facts of adsorption solvent, adsorption kinetics and adsorption selectivity were studied in the static adsorption methods. The scatchard plot suggested that the template-polymer system has two site of adsorption behavior with adsorption capacities of 1.170 mg/g and 6.244 mg/g, respectively. The (allyl-β-CD)-MIPs were used as selective sorbents for the solid-phase extraction (SPE) in the dynamic methods. The results indicated that (allyl-β-CD)-MIPs have specific recognition selectivity and excellent adsorption affinity for DPP. Finally, the (allyl-β-CD)-MIPs were used for molecularly imprinted solid-phase extraction (MISPE) to analyze the phthalates in cow milk.