Molecularly Imprinted Electrochemical Sensor Based on Nitrogen-doped Molybdenum Carbide Nanosphere for Trace Analysis of Resveratrol.

Abstract

A novel molecularly imprinted electrochemical sensor based on nitrogen-doped molybdenum carbide(N-Mo2 C) nanosphere was fabricated for trace analysis of resveratrol in this work. N-Mo2 C with large specific surface area and good electrical conductivity was introduced to construct a sensitive imprinting platform. Molecularly imprinted polymer film was prepared through a simple electropolymerization method using resveratrol as the template molecule and o-phenylenediamine as the functional monomer. The sensor shows great analytical performance in the concentration range of 10-9  mol L-1 to 10-4  mol L-1 and the detection limit is as low as 4.37×10-10  mol L-1 . The sensor also has the advantages of good selectivity, reproducibility and stability, which opens a new way for the application of molecularly imprinted electrochemical sensors in the field ofbiomedicine detection.