Abstract
AbstractThe human major histocompatibility complex (MHC) class I chain-related genes A and B (MICA and MICB) are located within the human leukocyte antigen (HLA) class I region of chromosome 6 (1). Their organization, expression, and products differ considerably from classical HLA class I genes (2). MIC proteins are considered to be markers of “stress” in the epithelia (3), and they act as ligands for cells expressing a common activatory natural killer cell receptor (NKG2D) (4). MIC proteins are also highly polymorphic (5), although the functional implications of this polymorphism remain unclear (6).KeywordsMajor Histocompatibility Complex ClassPolymerase Chain Reaction AmplificationHuman Leukocyte Antigen ClassExternal DomainHuman Major Histocompatibility ComplexThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
