Abstract
The oxidized phospholipid oxPAPC, an oxidation product of polyunsaturated 1-palmitoyl-2-arachidonylphosphatidylcholine (PAPC), has unique biological properties that include driving inflammation in select cell types. However, the underlying mechanisms by which oxPAPC exerts its effects on cellular function are unclear. Here we investigate the effects of oxPAPC (a mixture of oxidized products), compared to PAPC, on molecular organization in model membranes composed of mixtures of 1,2-dipalmitoylphosphatidylcholine (DPPC) and cholesterol that serve as a proxy for lipid rafts.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
