Abstract
Spreading of antibiotic resistance genes producing bacteria among patients usually caused potentialinfections for human with high morbidity and mortality especially Klebsiella pneumoniae and the fastdevelopment of Multi-drug resistant (MDR) strains has significantly increased and can be quite problematic.Thus, the current study was aimed to determine the prevalence of antibiotic resistance genes (?-lactamase)among K. pneumoniae isolates. Methods: Fifty K. pneumoniae isolates were collected from sputum samplesfor patients suffered respiratory infection. The detection of resistance genes (blaSHV, blaVIM, bla IMP)was performed by polymerase chain reaction (PCR). Results: The frequency of ?-lactamase-positive K.pneumoniae was 28%, and the prevalence of the blaSHV, blaVIM and blaIMP genes was 100%, 0% and 0%respectively. Conclusions: These results ?-lactamase genes believing multi-drug resistance genes. This helpto decrease treatment problems as a result of resistant bacterial infections and prevention of transmission ofdrug resistance by rapid discovery infection-control programs.
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