Abstract
Klebsiella pneumoniae (K. pneumoniae) isolates are often multidrug-resistant (MDR) and clones producing extended-spectrum beta-lactamases (ESBL) are increasingly reported all over the world. This study aimed to determine drug-susceptibility profiles and characterize ESBL genes in clinical strains of K. pneumoniae in an university teaching hospital of Dakar. Sixty-six ESBL-producing K. pneumoniae strains were selected for this study and subjected to the Kirby-Bauer disk diffusion method and standard polymerase chain reaction (PCR) for the screening of major ESBL genes (blaCTX-M, blaCTX-M-9, blaCTX-M-15, blaCTX-M-25, blaOXA-1, blaTEM, blaSHV).
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