Molecular Biology in Orthopaedics

Abstract

Randy N. Rosier and Christopher H. Evans, editors. Rosemont, Illinois: American Academy of Orthopaedic Surgeons; 2003. 447 pages. $115.00 ($95.00 AAOS member). During the last decade, phenomenal discoveries have been made in molecular biology, and powerful new methods have been developed for elucidating the role of abnormalities in gene expression in the pathogenesis of human diseases. Scientists have appreciated the implications of these new developments. They understand that we have entered a new era in biomedical research, and they have applied this new knowledge and methodology in diverse areas of orthopaedic research, particularly to studies of the biologic processes that are involved in the formation of cartilage and bone during development and in the repair of bone in the adult. This excellent monograph provides extensive information regarding recent developments in our understanding of the molecular biology of the musculoskeletal system. The monograph is based on the proceedings of a workshop called “Molecular Biology in Orthopaedics,” which was held in September 2001. More than fifty scientists …