Abstract
The review article provides evidence that mitochondrial dysfunction plays an important role in the initiation and development of atherosclerosis. Such aspects as the mechanism of mitochondrial oxidative dysfunction, the formation of reactive forms of oxygen radicals, the regulation of their formation and their «targets», the mechanisms of vascular dysfunction and atherosclerosis associated with mitochondrial dysfunction, the formation of free radicals and the role of mitochondrial dysfunction with various risk factors for atherosclerosis.
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