Abstract
AbstractUntil now no synthetic polymer surface was available suitable for cardiovascular implantation which effectively prevents microthrombosis for a long time. The presented concept of our work is to develop a polymer surface to promote the growth of a durable endothelial cell monolayer which would be formed on the prothesis prior to implantation. A microporous polyetherurethane foil is being used as carrier polymer for the cell monolayer. Suitable functional groups are grafted on the polymer surface by plasma polymerization. The success of the first modification steps is followed by ESCA‐analysis and scanning electron microscopy. The modified carrier polymer is the starting material for covalent binding of biopolymers which react as adhesion supporter between the synthetic polymer surface and the endothelial cells.
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