Abstract

In Japan, most of gout patients are adults, and the prevalence of gout has increased markedly since the 1960s. This phenomenon is thought to be attributed to the westernization of the Japanese diet since 1955. Monitoring the intake of nutrients and foods in Japanese people is essential in the prevention of gout. The objective of this article is to propose a preventive method for gout through the evaluation of recent dietary habits in Japanese people. In this article, the author shows the relationship between the number of gout patients and food intake in Japanese people and suggests modification of food intake for the prevention of gout in Japanese people referencing the results of clinical research reported. The author used the data of the Comprehensive Survey of Living Conditions in Japan for the number of gout patients (1986-2016) and the data of the National Health and Nutrition Survey in Japan (1946-2017) for the intake of foods. The relationship between the number of gout patients and food intake in Japanese people was examined. Modification of food intake for the prevention of gout is suggested as follows: limiting the intake of meat, organ meats high in purine content (e.g., liver, kidney), confectioneries (sugary foods including desserts and sweets), and sugar-sweetened beverages; limiting alcohol beverage consumption; limiting or decreasing intake of oils and fats, and seasonings and condiments (soy paste, soy sauce, and sauce); encourage intake of fiber-rich foods (e.g., cereals, whole grains, high-fiber bread), eggs, milk and dairy products (especially low-fat dairy products), legumes, seeds and nuts, fruit, vegetables, and coffee. The above dietary habits for the prevention of gout with proper choices of foods may also play a helpful role in the prevention of gout.

Highlights

  • This article shows the relationship between the number of gout patients and food intake in Japanese people and suggests modification of food intake for the prevention of gout in Japanese people referencing the results of clinical research reported

  • Excessive intake of meat was associated with increased risk of gout attacks [39, 40]. These results suggest that decrease in daily meat intake in Japanese people is essential for the prevention and suppression of gout

  • In epidemiological studies, increased intake of seafood was associated with increased serum uric acid (SUA) concentrations [12, 22, 26, 27], hyperuricemia risk [26, 28, 29, 31, 33, 46,47,48,49], and gout risk [22, 28, 36, 37]. These results suggest that decrease in daily seafood intake in Japanese people is essential for the prevention of gout

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Summary

Introduction

To explore means of the dietary control for the prevention of gout, the author [1,2,3] previously suggested modification of nutrient intake for the prevention of gout in Japanese people as described below: energy-providing nutrient balance (percentages of proteins, fats, and carbohydrates of total energy intake) should be within the range of the tentative dietary goal for preventing lifestyle-related diseases (DG); reduce fat (especially animal fat) intake and maintain the mean ratio of energy intake from saturated fatty acids in total energy intake (Saturated fatty acids/Energy) within the range of the tentative dietary goal for preventing lifestyle-related diseases (DG); replacement of saturated fatty acids with mono- and polyunsaturated ones (especially n-3 polyunsaturated fatty acids); avoidance of excessive intake of saturated fatty acids and cholesterol; limiting or decreasing salt intake; pay attention to sucrose and fructose intake; increase intake of dietary fiber, vitamin A, vitamin B1, vitamin B2, vitamin B6, calcium, potassium, magnesium, and zinc; and maintenance of good hydration. Koguchi [4] reported the review that summarizes the results of clinical research (clinical trials and epidemiological studies) of the association between SUA concentration, hyperuricemia risk, or gout risk and dietary factors. From the results of trends in food intake in Japanese people, it is necessary to recognize what food intake is important for the prevention of gout. This article shows the relationship between the number of gout patients and food intake in Japanese people and suggests modification of food intake for the prevention of gout in Japanese people referencing the results of clinical research reported. Takashi Koguchi: Modification of Dietary Habits for Prevention of Gout in Japanese.

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