MODERN PECULIARITIES OF PEDIATRIC CHRONIC GASTRODUODENITIS COURSE

Abstract

Aim. To study the modern clinicolaboratory peculiarities of chronic gastroduodenitis course in children. Materials and methods. Fifty five children aged 5-15 years with chronic gastroduodenitis were under observation. Complex clinicolaboratory study including biochemical blood analysis, ultrasonic investigation of abdominal cavity organs, pH-metry, fibrogastroduodenoscopy was carried out. Results. Chronic gastroduodenitis among the observed children was often associated with biliary dysfunction (80 %) and reactive changes in the pancreatic gland (72,7 %). Clinical picture of chronic gastroduodenitis was characterized by the predominance of abdominalgias (100 %), presence of dyspeptic syndrome in the form of nausea (78,2 %), eructation (76,4 %), appetite disorders (60,0 %). Children aged 5-9 years, more often had diarrhea ( p = 0,028) and periumbilical localization of abdominalgias ( p = 0,03), but in adolescents there was more often observed heartburn ( p = 0,047) and apigastral localization of abdominalgias ( p = 0,037). Elevated acid-forming gastric function was stated in 58,2 % of cases. Helicobacter pylori was revealed in 34,5 % of children. More frequently superficial gastroduodenitis (85,5 %) was diagnosed. Pangastritis was registered in 96,4 % of children, panduodenitis - in 98,2 %. Conclusions. Chronic gastroduodenitis extremely seldom occurs in the form of isolated disease. The whole gastrointestinal tract with manifestation of biliary dysfunctions, pancreatic reactive changes, digestive motor disorders is involved into the pathological process. Early diagnosis of this disease, followed by prophylactic measures to prevent the development of associated pathology of different parts of gastrointestinal tract is required.