Abstract
Aquametric and thermodynamic characteristics of the new excipients lactose 80 m, agglomerated lactose (tablettose 80), and microcellulose 101 – 200 were studied. Microcellulose 101 – 200 was more hygroscopic than both lactose derivatives at all values of relative humidity. Lactose 80 m and tablettose 80 had different thermodynamic characteristics that were probably explained by differences in the technology of raw material production. Comparative analysis of trace elements in the studied excipients by atomic absorption spectroscopy (AAS) and x-ray fluorescence (XRF) methods was carried out. Both methods gave comparable results but XRF gave high reproducibility and did not require long sample preparation. The toxicological safety of the analyzed compounds was established.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
