Abstract

Sepsis is among the most lethal diseases in Hungary. While there were 2659 septic events treated in intensive care units (ICU) in Hungary in 2001, 42.7% of the treated patients died owing to sepsis. Obviously, this figure calls attention to the need of measuring the effectiveness and efficiency of sepsis treatment. There is a considerable amount of information related to the effectiveness of different treatment alternatives. In our study we aimed to assess the cost-effectiveness of sepsis treatment in Hungary for the year 2001.

Highlights

  • Activation of the HPA axis occurs in order to control potentially deleterious effects of systemic inflammation during sepsis

  • A recent study showed that vascular endothelial damage was the primary cause of multiple organ failure (MOF) in patients with thrombopenia and that humoral mediators played a major role in the development of this process [1]

  • We aimed to evaluate the relation between the platelet counts (PC), the C-reactive protein and plasma fibrinolytic capacity in intensive care unit (ICU) patients

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Summary

Introduction

Activation of the HPA axis occurs in order to control potentially deleterious effects of systemic inflammation during sepsis. The aim of the study was to evaluate the effects of PEEP on intrathoracic blood volumes and cardiac function measured by the COLD system in ARDS patients. The objective was to identify risk factors and outcome of pregnant women who required intensive care This pilot study aims to find stress (S) and other personality traits (physical symptoms [PS], anger [A]) among the ICU staff, and any existing correlation between them and length of working time (LWT) in the ICU and with educational level (EDL). The role of Drotrecogin alfa (activated) (recombinant human activated protein C [rhAPC]) in modulating microvascular coagulation through the inhibition of thrombin generation has been well studied in experimental and clinical settings of severe sepsis, little is known about its direct anti-inflammatory effects on vascular endothelial cells. The aim is to determine whether an effective lifestyle adaptation program post CABG could enhance the quality of life of the CABG patient

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