Abstract
An intra-host epidemiological model is formulated for the co-infection of drug-sensitive and drug-resistant malaria parasites to examine the impact of aggressive treatment on the effect of competitive release in an infected host. The analysis of the existence of equilibrium and their stability of the model is conducted, and the results reveal that the intra-host competition and treatment play a key role in the prevalence of drug-resistant strains. The mathematical outcomes qualitatively match the experimental fact, that the rapid elimination of drug-resistant strains could promote the very evolution it is intended to retard.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call