Abstract
When trying to meet final product specifications for porosity of granules made using high-shear granulation there are many choices for the formulation recipe and processing conditions. This paper presents the concept of a Critical Packing State of the primary particles forming a granule and the associated Limiting Binder Ratio, which allows granule consolidation to be modelled. The effect on consolidation of varying the following processing parameters is explained: Mixing intensity, mixing time and binder addition method. The effects of varying the following aspects of the formulation recipe are explained: Primary particle type, shape and size distribution, binder type and binder: solid ratio.
Published Version
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