Abstract

SummaryFor modelling the location of pyramidal cells in the human cerebral cortex, we suggest a hierarchical point process in that exhibits anisotropy in the form of cylinders extending along the z‐axis. The model consists first of a generalised shot noise Cox process for the xy‐coordinates, providing cylindrical clusters, and next of a Markov random field model for the z‐coordinates conditioned on the xy‐coordinates, providing either repulsion, aggregation or both within specified areas of interaction. Several cases of these hierarchical point processes are fitted to two pyramidal cell data sets, and of these a final model allowing for both repulsion and attraction between the points seem adequate. We discuss how the final model relates to the so‐called minicolumn hypothesis in neuroscience.

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