Abstract
Bacteriocins are ribosomally synthesized antimicrobial peptides displaying different mode of action. Non pathogenic Bacillus licheniformis are usually associated with plants and produce several bacteriocins. This work looks at drug designing strategies using protein modelling and bioinformatics tools. In this study computational modelling and docking studies were carried out using the 13 amino acid sequence of a previously characterized thermostable bacteriocin, BL8 produced by B. licheniformis strain BTHT8. These analyses enabled the understanding of the structure of BL8 protein domain, which was noted to belong to alpha + beta protein fold family. In addition, the docking study predicted that BL8 has properties of angiotensin-converting enzyme (ACE) inhibitor.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
