Abstract
Copolymers of acrylic acid and acryloyl nucleosides were obtained by the interaction of polyacrylic anhydride with uridin, N-acetyl derivatives of adenosin, cytidine and guanosine. In contrast to polyacrylic acid, copolymers with neutral pH and an ionic strength of 0·2 form molecular associates observed as threads with an electron microscope. On increasing temperature to 100°, followed by sudden cooling and increase of pH to 12, the thread structures were transformed to spheres. With slow cooling and neutralization the thread-like structure is restored. These transformations are similar to those taking place with nucleinic acid during denaturing, renaturing and suggest that the association of copolymer molecules is due to the formation of hydrogen bonds in conjunction with the bases of nucleosides.
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