Abstract
An essential part of the innate immune defenses is the phagocytosis of invading pathogenic microbes by professional phagocytes and their subsequent digestion within the phagosome. It is often forgotten that not all pathogens surrender without a fight—in particular, some species succeed in surviving inside the phagosome. These intracellular pathogens have evolved various individual strategies to counteract the killing mechanisms of the host cell, many of which have been poorly understood.
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