Mobile Phone Automated Messaging Service’s and the Fulfilment of Planned Clinical Appointments: Lessons from an Ebola Clinical Study in Kambia District, Sierra Leone

Abstract

Introduction: The Ebola vaccine Deployment, Acceptance, and Compliance (EBODAC) project was established to develop a communication and community engagement strategy, including the development of appropriate technology, to maximize Ebola vaccination impact in the targeted population both in support of clinical trials and in the broader vaccination program beyond the clinical trial. EBODAC supported the EBOVAC-Salone trial in Kambia district in Sierra Leone to ensure that the novel prime-boost vaccine regimen is well accepted and successfully used in the context of clinical trials; while also preparing to maximize the impact of the potential deployment of a future Ebola vaccination program. The Mobile Technology for Community Health (MOTECH) platform was utilized and customized to help ensure compliance with the prime-boost vaccination regimen. Its main role was to support the communications and reminders surrounding the Ebola vaccine trial through an automated message service to participants’ mobile phones as Interactive Voice Responses (IVR) and SMS (Short Message Service) messages. Methods: The study was cross-sectional and adopted qualitative and quantitative research methods. The design was constructed to provide a representation of different user segments. The sample size was not constructed to provide statistical differences or detect differences in impact among groups but was simply designed to provide insights into how study participants interacted with the technology. Eligibility criteria involved randomly selecting participants from those that: a) received IVR and SMS and didn’t miss an appointment (booster compliant), b) received IVR and SMS and missed an appointment (booster non-compliant), c) received no IVR and SMS and didn’t miss or missed an appointment (MOTECH non-user). Quantitative information was entered in well-designed data entry templates. All participants’ names were anonymized for data analysis. Results: All the respondents, (n=81) revealed liking both the IVRS and SMS messages and majority of these, 80.2% (n=65) reported that IVR was very easy to understand. Respondents 47.5% (n=45) were comfortable receiving IVR, as opposed to 35.8% (n=29) preferred both text and voice messages. It was also found that 74.1% (n=60) of the respondents who were sent visit reminder messages never missed clinic appointment and 81.5% of those that received information preferred to know how to protect themselves from the disease. Conclusion: The EBOVAC-Salone automated voice messages contributed to valuable learning about areas of improvement for the MOTECH that will be of great importance for future outbreaks and medical interventions.