Mo1042 Incidence and Predictors of Lymph Nodal Metastases in Patients With Cholangiocarcinoma in the United States

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A S L D A b st ra ct s Multivariate logistic regression analyses showed that younger age, African-American race, scirrhous, spindle cell or pleomorphic histology and severe fibrosis score were independent factors associated with AFP-elevated HCC. Conclusions: Elevated pretreatment serum AFP level (i.e. A-stage) is an AJCC-stage independent poor prognostic factor in HCC. We recommend the incorporation of A-stage within the current TNM-based AJCC staging system to enhance estimates of survival and aid therapeutic decision-making, especially in earlier stage HCC.