Mitral Valve Prolapse In Atrial Septal Defect

Abstract

Mitral valve prolapse is encountered at a rate of 25-95 % in patients with atrial septal defect. In this study, we aimed at obtaining physiopathological patterns causing mitral valve prolapse in patients with atrial septal defect by comparing the patients with atrial septal defect but no mitral valve prolapse (Group 1) to those with atrial septal defect and mitral valve prolapse (Group 2) in accordance with the following echocardiographic parameters: diastolic interventricular septum thickness, diastolic left ventricular posterior wall thickness, left ventricular ejection fraction, left ventricle end-diastolic diameter, left ventricle end-systolic diameter, right ventricular out-flow tract diameter, right ventricular in-flow tract diameter and mitral valve area calculated with pressure half-time. There were significant differences between the two groups in terms of diastolic interventricular septum thickness and left ventricular posterior wall thickness (10±2.16 to 8.7±0.38 and 9.27±l.56 to 8.1±l.18, p<0.0035 and p<0.0006 respectively). The left ventricular ejection fraction was found to be significantly high in patients with atrial septal defect and mitral valve prolapse (72.26±5.48 to 69.06±6.23, p<0.011).