Abstract
Mitosis Detection in Phase Contrast Microscopy Image Sequences of Stem Cell Populations: A Critical Review
Highlights
AND RELATED WORK: State-of-the-art methods for mitotic event detection in microscopy image sequences can be generally classified into the three following categories
The detection of mitotic cells can provide valuable information to improve the performance of tasks such@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 2 | Jan-Feb 2018
Based on the changes of visual appearance of stem cells in phase contrast microscopy images, mitosis of stem cells can be segmented into four stages, and each of them is related to biological phases in the cell circle: 1. Interphase stage, when the cells still looks normal in appearance; 2
Summary
The information provided by mitosis detection can be further utilized in biological and medical applications such as cell culture monitoring, stem cell manufacturing, drug development, tissue engineering and so on. The detection of mitotic cells can provide valuable information to improve the performance of tasks such@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 2 | Jan-Feb 2018. Based on the changes of visual appearance of stem cells in phase contrast microscopy images, mitosis of stem cells can be segmented into four stages, and each of them is related to biological phases in the cell circle: 1. Separation of daughter cells, when two daughter cells get completely sepa-rated after cytokinesis is completed. These four stages in the visual appearance transition are illustrated in fig[1]
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