Abstract

Mitochondria in neurodegenerative diseases.

Highlights

  • The mitochondrion consists of 3000 proteins. 3% among them are responsible for creating 95% ATP needed for cells

  • Exercise could en‐ hance autophagy‐lysosomal pathway and decrease mitochondrial vacuolization caused by chloroquine through restoring autophagic flux.[2,3]

  • Mitochondrial fission and fusion impact numerous cellular func‐ tions, and neurons are sensitive to perturbations in mito‐ chondrial dynamics

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Summary

Introduction

The mitochondrion consists of 3000 proteins. 3% (about 100 pro‐ teins) among them are responsible for creating 95% ATP needed for cells. Mitochondrial fission and fusion impact numerous cellular func‐ tions, and neurons are sensitive to perturbations in mito‐ chondrial dynamics.

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Conclusion
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