Misoprostol combined with oxytocin in treatment of hemorrhage after cesarean section

Abstract

Objective To explore the effect of misoprostol combined with oxytocin in the treatment of hemorrhage after cesarean section. Methods 84 puerperae undergoing cesarean section at our hospital from January, 2013 to January, 2016 were selected as study objects and were divided into an observation group and a control group according to different treatment methods. The observation group rectally took misoprostol and were treated with oxytocin; and the control group were treated with oxytocin. The hemostatic effect was observed in both groups. Results The total effective rate was 95.2% in the observation group and was 78.6% in the control group, with a statistical difference (P 0.05) . The intraoperative bleeding volume and 2 h postpartum hemorrhage were (958.2 ± 125.6) ml and (81.3 ± 13.1)ml in the control group and were (558.7 ± 86.5) ml and (42.6 ± 10.8) ml in the observation group, with statistical differences (all P<0.05). The incidence of complications was significantly lower in the observation group than in the control group, with a statistical difference (P<0.05). Conclusion Oxytocin combined with rectal misoprostol has significant hemostatic effect for patients with cesarean section and is a relatively simple method, so it is worth being clinically generalized. Key words: Misoprostol; Oxytocin; Postpartum hemorrhage; Cesarean section