Abstract

To the Editor:— The letter by Dr. Garrett takes issue with the following statement: If a significant rise in titer occurs during the pregnancy, this is definite proof that the fetus in utero is Rh positive, and an erythroblastotic baby is to be expected, even though the father may be heterozygous. Evidence for this statement can most easily be found in my recent book, Rh-Hr Blood Types (New York, Grune & Stratton, Inc., 1954, pp. 143-159). The following table summarizes the data from that section of my book. As the table demonstrates, in not one of the 12 cases in which the baby proved to be Rh negative was there a significant rise in the maternal Rh antibody titer during the pregnancy; in 13 out of 55 cases in which the baby subsequently proved to be Rh positive, there was a definite rise in titer. Since 1951, when this material was published, the number of cases studied by me

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