Abstract
<p>Bovine Mastitis is an infection of the mammary glands that represents important economic losses in milk production. As in other pathologies, medicinal plants emerged as an important alternative for treatment of this condition. In this sense, the aim of this study was to investigate the antioxidant activity of the extract of <em>Mentha arvensis</em> L. on the erythrocytes of healthy dairy cows (P1); of dairy cows with mastitis without previous treatment (P2); and of dairy cows with mastitis and previously treated with antibiotics (P3). The levels of Thiobarbituric Acid Reactive Substances (TBARS), of the protein carbonylation (PC) and reduced glutathione (GSH) were analyzed in the cows’ erythrocytes before and after treatment with the extract of Mentha. This study demonstrated an occurrence of oxidative stress in the cows with mastitis. The mint extract promoted an increase in GSH levels combined with a decrease in the levels of oxidative markers, especially in cows with mastitis without previous antibiotic treatment.</p>
Highlights
Bovine mastitis is considered one of the most important diseases of dairy cattle in the world, as it is the main cause for economic loss to milk producers everywhere
In the event of such imbalance, there may be oxidative damage in cells and tissues of animals, to the point of engendering the loss of biological functions important for homeostasis (Pisoschi & Pop, 2015). This may be demonstrated by the oxidation of the cell membrane lipid layer, leading to increased levels of Thiobarbituric Acid Reactive Substances (TBARS) and protein carbonyls (PC), which can be quantified by using the spectrophotometric method
The present study aims to investigate the antioxidant effect of the Mentha arvensis L. extract in the erythrocytes of dairy cows suffering from mastitis by using tests “in vitro”
Summary
Bovine mastitis is considered one of the most important diseases of dairy cattle in the world, as it is the main cause for economic loss to milk producers everywhere. The authors highlight the need to supplement dairy cattle with antioxidants such as vitamin E, beta-carotene, glutathione, urate, among others These findings emphasized that breast edema may be caused by “oxidative stress”, as reactive oxygen metabolites are not well controlled or metabolized by the body in such conditions (Miller et al, 1993b). In the event of such imbalance, there may be oxidative damage in cells and tissues of animals, to the point of engendering the loss of biological functions important for homeostasis (Pisoschi & Pop, 2015) This may be demonstrated by the oxidation of the cell membrane lipid layer, leading to increased levels of Thiobarbituric Acid Reactive Substances (TBARS) and protein carbonyls (PC), which can be quantified by using the spectrophotometric method. The elevation of blood biomarkers indicates increased protein and lipid oxidation levels (Barbosa et al, 2010)
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