Abstract
Systemic lupus erythematosus is an autoimmune disorder characterized by microvascular inflammation, usually causing multiple organ dysfunction including the heart and kidneys. It commonly causes valvular heart disease, mitral valve insufficiency being the most common. SLE patients are prone to develop premature coronary artery disease. Some patients who are positive for Anti-Ro/La antibodies develop complete heart block. We describe the case of severe mitral regurgitation with Libman-sacks endocarditis in a patient diagnosed with SLE. She underwent minimally invasive mitral valve replacement.
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