Abstract
Objective. Improve the effectiveness of surgical treatment in patients with bilateral destructive pulmonary tuberculosis by mini-invasive resection and collapse therapy. Materials and Methods: Retrospective analysis of 222 patients ’ cards with bilateral destructive pulmonary tuberculosis who were treated in the period from 1995 to 2014 in the thoracic department of Dnepropetrovsk regional clinical therapeutic and prophylactic association Phthisiology. Patients were divided into 2 groups: basic (111 patients who underwent mini-invasive surgery) and control (111 patients, who underwent standard surgical approach). The distribution of patients in investigated groups was representative by the majority of parameters. Results and discussion. The average duration of simultaneous bilateral VATS lung resections was 1,90 ± 0,12 hour, standard thoracotomies - 2,13 ± 0,19 per hour, estimated blood loss was 234±5,20ml and 433±3,70ml respectively. The average postoperative time in-patient was 52,40±2,63 days in basic and 80,10±3,58 days in the control group. Number of p ostoperative complications after lung resection with VATS was significantly lower (1.6 times), as compared with standard surgical approach. Volume of blood loss less than 400 ml was 93,40±3,20% in basic and 72,60±4,80% in the control group, the amount of intraoperative complications reduced by 2.2 times. Complete clinical response (decontamination and closing of cavities) have been achieved in patients of the basic group by 1.6 times more often. Conclusions: For patients with bilateral pulmonary tuberculosis to perform mini-invasive surgical approach is the best option. Mini-invasive interventions with VATS due to its good abilities to visualize tissue s and anatomical structures may significantly decrease the amount of intraoperative blood and plasma loss in the first postoperative day. It leads to the stabilization of tuberculosis process in the contralateral lung, responsible for overall positive clinical effect in patients with advanced pulmonary tuberculosis. For patients with bilateral destructive pulmonary tuberculosis, who can’t undergo resection, performing a mini-invasive therapeutic thoracoplasty is the optimal approach.
Highlights
Mini-invasive resection and collapse therapy in patients with bilateral pulmonary tuberculosis
Retrospective analysis of 222 patients' cards with bilateral destructive pulmonary tuberculosis who were treated in the period
Patients were divided into 2 groups
Summary
Ȼɭɥɢ ɜɢɜɱɟɧɿ ɿɫɬɨɪɿʀ ɯɜɨɪɨɛ 222 ɩɚɰɿɽɧɬɿɜ, ɨɩɟɪɨɜɚɧɢɯ ɭ ɥɟɝɟɧɟɜɨ-ɯɿɪɭɪɝɿɱɧɨɦɭ ɜɿɞɞɿɥɟɧɧɿ ȾɈɄɅɉɈ «Ɏɬɢɡɿɚɬɪɿɹ» ɭ ɩɟɪɿɨɞ 1995-2014 ɪɪ. ɡ ɩɪɢɜɨɞɭ ɞɜɨɛɿɱɧɨɝɨ ɞɟɫɬɪɭɤɬɢɜɧɨɝɨ ɬɭɛɟɪɤɭɥɶɨɡɭ ɥɟɝɟɧɶ. Ɉɫɧɨɜɧɭ ɝɪɭɩɭ ɞɨɫɥɿɞɠɭɜɚɧɢɯ ɫɤɥɚɥɢ 111 ɯɜɨɪɢɯ ɭ ɜɿɰɿ ɜɿɞ 18 ɞɨ 58 ɪɨɤɿɜ, ɭ ɹɤɢɯ ɛɭɥɢ ɜɢɤɨɪɢɫɬɚɧɿ ɦɿɧɿ-ɿɧɜɚɡɢɜɧɿ ɦɟɬɨɞɢ ɯɿɪɭɪɝɿɱɧɨɝɨ ɥɿɤɭɜɚɧɧɹ ɿɡ ɡɚɫɬɨɫɭɜɚɧɧɹɦ ɦɿɧɿɞɨɫɬɭɩɭ ɩɿɞ ɤɨɧɬɪɨɥɟɦ ɜɿɞɟɨɬɨɪɚɤɨɫɤɨɩɿʀ. Ⱦɨ ɝɪɭɩɢ ɩɨɪɿɜɧɹɧɧɹ ɭɜɿɣɲɥɢ 111 ɩɚɰɿɽɧɬɿɜ, ɨɩɟɪɨɜɚɧɢɯ ɡɿ ɫɬɚɧɞɚɪɬɧɢɯ ɞɨɫɬɭɩɿɜ ɡɚ ɡɚɝɚɥɶɧɨɩɪɢɣɧɹɬɢɦɢ ɦɟɬɨɞɢɤɚɦɢ. Ɂɚɥɟɠɧɨ ɜɿɞ ɯɚɪɚɤɬɟɪɭ ɜɢɤɨɧɭɜɚɧɢɯ ɜɬɪɭɱɚɧɶ, ɫɬɭɩɟɧɹ ʀɯ ɪɚɞɢɤɚɥɶɧɨɫɬɿ ɿ ɩɪɨɝɧɨɡɭ ɩɨɞɚɥɶɲɨɝɨ ɤɨɧɫɟɪɜɚɬɢɜɧɨɝɨ ɥɿɤɭɜɚɧɧɹ ɨɛɢɞɜɿ ɝɪɭɩɢ ɛɭɥɢ ɪɨɡɩɨɞɿɥɟɧɿ ɧɚ ɤɿɥɶɤɚ ɩɿɞɝɪɭɩ. Ɫɩɪɢɹɬɥɢɜɨɝɨ ɩɪɨɝɧɨɡɭ ɤɨɧɫɟɪɜɚɬɢɜɧɨɝɨ ɥɿɤɭɜɚɧɧɹ (ɫɮɨɪɦɨɜɚɧɿ ɮɿɛɪɨɡɧɿ ɤɚɜɟɪɧɢ, ɚɛɨ ɬɭɛɟɪɤɭɥɶɨɦɢ ɡ ɪɨɡɩɚɞɨɦ), ɚɥɟ ɡɚ ɩɨɲɢɪɟɧɿɫɬɸ ɩɪɨɰɟɫɭ ɿ ɮɭɧɤɰɿɨɧɚɥɶɧɨɦɭ ɫɬɚɧɭ ɛɭɥɨ ɦɨɠɥɢɜɟ ɜɢɤɨɧɚɧɧɹ ɪɚɞɢɤɚɥɶɧɢɯ ɞɜɨɛɿɱɧɢɯ ɨɩɟɪɚɰɿɣ. Ɍ II ɩɿɞɝɪɭɩɭ ɛɭɥɢ ɜɤɥɸɱɟɧɿ ɯɜɨɪɿ, ɳɨ ɦɚɥɢ ɩɨɤɚɡɚɧɧɹ ɞɥɹ ɞɜɨɛɿɱɧɢɯ ɤɨɥɚɩɫɨɯɿɪɭɪɝɿɱɧɢɯ ɜɬɪɭɱɚɧɶ ɚɛɨ ɨɞɧɨɛɿɱɧɢɯ ɩɪɢ ɡɛɟɪɟɠɟɧɧɿ ɬɟɪɚɩɟɜɬɢɱɧɢɯ ɪɟɡɟɪɜɿɜ ɥɿɤɭɜɚɧɧɹ ɤɨɧɬɪɥɚɬɟɪɚɥɶɧɨʀ ɥɟɝɟɧɿ. Ȼɿɥɶɲɿɫɬɶ ɩɚɰɿɽɧɬɿɜ ɭ ɩɟɪɲɿɣ ɩɿɞɝɪɭɩɿ ɨɩɟɪɨɜɚɧɿ ɡ ɩɪɢɜɨɞɭ ɬɭɛɟɪɤɭɥɨɦ ɡ ɪɨɡɩɚɞɨɦ (67,5%), ɭ ɞɪɭɝɭ ɝɪɭɩɭ ɭɜɿɣɲɥɢ ɯɜɨɪɿ ɡ ɮɿɛɪɨɡɧɨ-ɤɚɜɟɪɧɨɡɧɢɦ ɬɭɛɟɪɤɭɥɶɨɡɨɦ (100%). Ȼɿɥɶɲɿɫɬɶ ɩɚɰɿɽɧɬɿɜ ɭ ɩɟɪɲɿɣ ɩɿɞɝɪɭɩɿ ɨɩɟɪɨɜɚɧɿ ɡ ɩɪɢɜɨɞɭ ɬɭɛɟɪɤɭɥɨɦ ɡ ɪɨɡɩɚɞɨɦ (67,5%), ɭ ɞɪɭɝɭ ɝɪɭɩɭ ɭɜɿɣɲɥɢ ɯɜɨɪɿ ɡ ɮɿɛɪɨɡɧɨ-ɤɚɜɟɪɧɨɡɧɢɦ ɬɭɛɟɪɤɭɥɶɨɡɨɦ (100%). (ɬɚɛɥ. 1)
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