Mineral Density and Markers of Bone Remodelling in Young Athletes in Response to Weightlifting Exercise: A Pilot Study

Fernando B Reyes,Julio M Brown,Rosa O Méndez Estrada,Rogelio R Enríquez,Héctor Manuel S Sainz,José Andre-Í S Sainz,Rosa Consuelo V Valle,Armando C Dosamantes

doi:10.2174/1875399x02114010124

Abstract

Background: Weightlifting is a practice that exerts a high degree of pressure on the skeleton when supporting large loads of weight. The practice of exercise contributes by improving bone mineral density (BMD) and can prevent problems associated with low BMD. Objective: The objective of the present study was to determine BMD and measure bone turnover using blood markers in weightlifting athletes in response to exercise. Methods: The study included 16 athletes and 16 controls of both sexes in the range of 18 to 22 years old. BMD was determined at the femoral neck, hip, lumbar spine, and Total Mineral Density (TMD). The value of the total mineral density (TMDV) was obtained from the sum of the BMD of the evaluated regions. Bone formation and resorption in blood were evaluated by Alkaline Phosphatase (ALP) and Acid Phosphatase (ACP), respectively. In addition, the concentration of urea and Creatine Kinase (CK) were determined. Results: The mean BMD of the lumbar spine and TMDV was of 1.2 g/cm2 in female and male athletes. In young people who did not practice weightlifting, BMD in the lumbar spine (0.9 g/cm2 in both groups) and TMDV (1.05 g/cm2 in women and 1.11 g/cm2 in men) were significantly lower (p <0.05). The activity in bone formation and CK in male athletes was twice as high compared to the other groups. The blood urea concentration in athletes (32.7- 38.0 mg/dL) was significantly higher (p <0.05) compared to the control groups (19.3-18.8 mg/dL). Conclusion: The practice of weightlifting benefits bone mass gain in the lumbar spine. These findings suggest that exercises in which high weight loads are supported promote bone turnover and mineralization to prevent bone weakening.

Highlights

Weightlifting is one of the practices that most involves the development of physical strength and power [1, 2]
The practice of weightlifting benefits bone mass gain in the lumbar spine. These findings suggest that exercises in which high weight loads are supported promote bone turnover and mineralization to prevent bone weakening
Some processes such as the decrease in the activity of the osteoblasts mandated for bone mineralization and the increase in the osteoclasts responsible for bone degradation cause an unfavorable imbalance for bone mineralization [7]

Summary

Introduction

Weightlifting is one of the practices that most involves the development of physical strength and power [1, 2]. Osteoporosis is an age-related disease characterized by low mineralization of the bones. Physical activity is essential for the correct development of the bone since the architecture and bone mass depend on the degree of pressure of the biomechanical load of the exercise [8]. Not practicing impact exercises on the bones can affect bone density and structure. Weightlifting is a practice that exerts a high degree of pressure on the skeleton when supporting large loads of weight. The practice of exercise contributes by improving bone mineral density (BMD) and can prevent problems associated with low BMD

Methods

Results

Conclusion