Abstract
Aqueous extract of Mimosa pudica flowers have been used for the synthesis of silver nanoparticles (MpFNp). MpFNp were characterized by UV–Visible spectroscopy, field emission scanning electron microscopy, Fourier transform infrared spectroscopy, zeta potential, energy dispersive X-ray spectroscopy, and particle size distribution by dynamic light scattering. MpFNp showed bactericidal activity at 3.125 µg/mL for E. coli (ATCC 25922), S. aureus (MTCC 1430), and 1.56 µg/mL for P. aeroginosa (ATCC 27853), 25 µg for antibiotic-resistant strains of Acinetobacter baumannii (TE1), Bacillus paramycoides (TE2), and Aeromonas veronii (TE3) isolated from tannery effluent. Antobiofilm activity was exhibited at lower concentration of MpFNp. The expression of AmpC gene was suppressed upon treatment with MpFNp. Thus, the synthesized nanoparticles can be formulated to control multidrug-resistant organisms.
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