Abstract
The migration of Hymenolepis microstoma in mice has been studied following (a) oral infection with cysticercoids and (b) surgical inplantation of artificially excysted larvae into host small intestine. During the initial establishment period (0–3 h p. i.), worms were never found farther than 35 cm behind the pylorus. Their anterior movement is already visible 24 h p. i. The massive entrance of the worms into the bile duct starts on day 5 and is virtually complete on day 8. The inplantation experiments have shown that anterior migration and thus survival are more and more endangered the farther the injection site. Orientation troubles start in small intestine section 4 (15–20 cm behind the pylorus). Only a minority of the worms inplanted in section 5 (20–25 cm behind the pylorus) are able to move forward. Worms brought into posterior sections are all eliminated. Techniques and results are discussed and, while other possible factors are taken into consideration, it is thought that bile is the main “homing factor”.
Published Version
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