Abstract

Migraine and cerebral small vessel disease (CSVD) are 2 common neurovascular diseases in clinical practice. Their pathogeneses are still not clear. Migraine may increase the risk of CSVD, and CSVD can also cause migraine attacks by triggering cortical spreading depression and other mechanisms. The relationship between the two diseases is mutual and complex, and is influenced by a variety of factors, but the mechanism of this potential relationship is not yet very clear. With further research, the reports about the relationship between migraine and CSVD are increasing. This article summarizes the pathophysiological mechanisms of migraine and CSVD and the correlation between both. Key words: Cerebral Small Vessel Diseases; Migraine Disorders; Cortical Spreading Depression; Magnetic Resonance Imaging; Risk Factors

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