Abstract
Background: 1,3-Aminooxygenated functional groups exhibit a variety of biological and pharmacological activities including nucleosides, antibiotics and HIV protease inhibitors. On the other hand, carbazole-containing molecules show antiviral, antimalarial and antitumor activity. However, to the best of our knowledge there are no reports available on the synthesis of amidoalkyl carbazolols. In this connection, we wish to report the synthesis of amidoalkyl carbazolol derivatives by one-pot threecomponent reaction. Keywords: Hydroxycarbazole, 1-amidoalkyl-2-carbazolol derivatives, microwave irradiation, three-component reaction, orthoquinone methide.
Published Version
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