Abstract

A general protocol for the synthesis of 2-heteroaryl-5-methoxyindoles has been developed utilizing a microwave-induced solid-supported Fischer indolization under controlled conditions This route uses 2-acetylpyridine as a model and 3-acetyl derivatives of cycloalkeno[ c]fused pyridines as the synthetic building blocks towards new 9-methoxyindolo[2,3- a]quinolizine alkaloids.

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