Abstract
AbstractEnzyme-catalyzed reactions are highly selective and can be carried out under ambient conditions, thus avoiding the extreme conditions used in chemical reactions which could cause various problems. Enzymes can be cloned and overexpressed and this feature, along with directed evolution of enzymes under desired process conditions, has led to the production of novel and highly efficient biocatalysts for the development of economical processes for pharmaceutical development. This article describes a number of key biocatalytic steps in synthesis and total synthesis.
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