Abstract

Experiments were performed on free tablet coating films to evaluate microwave energy as a potential drying source for aqueous tablet film coating. Free films of 4 formulations containing either hydroxypropyl methyl cellulose or methyl cellulose were prepared using a conventional microwave oven as the drying source. Oven drying at various temperatures and convective air drying in the microwave oven at zero power setting were used as controls. Microwave drying rates were 2–22 times faster than controls. The physical properties of the films were not adversely affected by microwave drying, as indicated by water vapor permeability and tensile strength/Young's modulus measurements. The results suggest that microwave drying could be used as a substitute for conventional hot air drying in aqueous film coating.

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