Abstract
A novel, highly efficient, eco-friendly, and quick microwave-assisted synthesis of 2, 4, 5- substituted imidazoles by one-pot cyclo condensation of acenaphthoquinone, aromatic aldehydes, and ammonium acetate was reported under solvent-free conditions using ammonium chloride as a catalyst with excellent yield. The present methodology offers several advantages, such as mild reaction conditions, easy workup, short reaction time, excellent yield, purification of products by the non-chromatographic method, and reproducibility in large-scale synthesis. Compounds were characterized by IR, 1HNMR, 13C NMR spectroscopy and their melting points were compared with the literature reports.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.